Posts in January 3, 2020

Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer.

Coffee EM, Faber AC, Roper J, Sinnamon MJ, Goel G, Keung L, Wang WV, Vecchione L, de Vriendt V, Weinstein […]
by Jatin Roper
on Jan 3
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Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation.

Martin ES, Belmont PJ, Sinnamon MJ, Richard LG, Yuan J, Coffee EM, Roper J, Lee L, Heidari P, Lunt SY, […]
by Jatin Roper
on Jan 3
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Priceless GEMMs: genetically engineered mouse models for colorectal cancer drug development.

RoperJ, Hung KE. Priceless GEMMs: genetically engineered mouse models for colorectal cancer drug development. Trends Pharmacol Sci. 2012 Aug;33(8):449–55. PMID: […]
by Jatin Roper
on Jan 3
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The effect of H. pylori eradication on meal-associated changes in plasma ghrelin and leptin.

Francois F, Roper J, Joseph N, Pei Z, Chhada A, Shak JR, Olivares A, Perez-Perez GI, Blaser MJ. The effect […]
by Jatin Roper
on Jan 3
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The dual PI3K/mTOR inhibitor NVP-BEZ235 induces tumor regression in a genetically engineered mouse model of PIK3CA wild-type colorectal cancer.

Roper J*, Richardson MP*, Wang WV, Richard LG, Chen W, Coffee EM, Sinnamon MJ, Lee L, Chen P, Bronson RT, […]
by Jatin Roper
on Jan 3
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The association of gastric leptin with esophageal inflammation and metaplasia.

Francois F, Roper J, Goodman A, Pei Z, Mourad M, Olivares de Perez A, Perez-Perez GI, Tseng CH, Blaser MJ.  […]
by Jatin Roper
on Jan 3
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Leptin and ghrelin in relation to Helicobacter pylori status in male veterans.

Roper J, Francois F, Shue PL, Mourad M, Pei Z, Olivares AZ, Perez-Perez GI, Tseng CH, Blaser MJ.  Leptin and […]
by Jatin Roper
on Jan 3
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The effect of laparoscopic gastric banding surgery on plasma levels of appetite-control, insulinotropic, and digestive hormones.

Shak J, Roper J, Perez-Perez GI, Tseng CH, Francois F, Gamagaris Z, Patterson C, Weinshel E, Fielding GA, Ren C, […]
by Jatin Roper
on Jan 3
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Helicobacter pylori stimulates gastric epithelial cell MMP-1 secretion via Cag-A-dependent and independent ERK activation.

Pillinger MH, Marjanovic N, Kim SY, Lee YC, Scher JU, Roper J, Izmirly P, Pillinger MY, Tolani S, Dinsell V, […]
by Jatin Roper
on Jan 3
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