Posts in January 5, 2020

Metabolic Teamwork in the Stem Cell Niche.

Roper J, Yilmaz ÖH. Metabolic Teamwork in the Stem Cell Niche. Cell Metab. 2017 May 2;25(5):993–4. PMID: 28467944 2017
by Jatin Roper
on Jan 5
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Bariatric Surgery Prior to Index Screening Colonoscopy Is Associated With a Decreased Rate of Colorectal Adenomas in Obese Individuals.

Kedrin D, Gandhi SCC, Wolf M, RoperJ, Yilmaz ÖH, Corey K, Khalili H, Stanford F, Gala M. Bariatric Surgery Prior […]
by Jatin Roper
on Jan 5
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High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.

Beyaz S*, Mana MD*, Roper J*, Kedrin D, Saadatpour A, Hong S-J, Bauer-Rowe KE, Xifaras ME, Akkad A, Pinello L, […]
by Jatin Roper
on Jan 5
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Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.

Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio II, Giannopoulou EG, Rago C, […]
by Jatin Roper
on Jan 5
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Colorectal cancer models for novel drug discovery.

Golovko D, Kedrin D, Yilmaz ÖH, Roper J*. Colorectal cancer models for novel drug discovery. Expert Opin Drug Discov. 2015;10(11):1217–29. […]
by Jatin Roper
on Jan 5
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Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.

Belmont PJ, Jiang P, McKee TD, Xie T, Isaacson J, Baryla NE, Roper J, Sinnamon MJ, Lee NV, Kan JL, […]
by Jatin Roper
on Jan 5
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Co-occurrence of idiopathic granulomatous hepatitis and primary biliary cirrhosis.

Paul S, Sepehr GJ, Weinstein B, RoperJ. Co-occurrence of idiopathic granulomatous hepatitis and primary biliary cirrhosis. Dig Dis Sci. 2014 […]
by Jatin Roper
on Jan 5
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Overview of genetically engineered mouse models of colorectal carcinoma to enable translational biology and drug development.

RoperJ, Martin ES, Hung KE. Overview of genetically engineered mouse models of colorectal carcinoma to enable translational biology and drug […]
by Jatin Roper
on Jan 5
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Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease.

Belmont PJ, Budinska E, Jiang P, Sinnamon MJ, Coffee E, Roper J, Xie T, Rejto PA, Derkits S, Sansom OJ, […]
by Jatin Roper
on Jan 5
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Combination PI3K/MEK inhibition promotes tumor apoptosis and regression in PIK3CA wild-type, KRAS mutant colorectal cancer.

RoperJ, Sinnamon MJ, Coffee EM, Belmont P, Keung L, Georgeon-Richard L, Wang WV, Faber AC, Yun J, Yilmaz ÖH, Bronson […]
by Jatin Roper
on Jan 5
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