Posts in Jatin Roper

Breakthrough Moments: Genome Editing and Organoids.

Roper J, Yilmaz ÖH.  Breakthrough Moments: Genome Editing and Organoids. Cell Stem Cell. 2019 Jun 6;24(6):841–2. PMID: 31173713 2019
by Jatin Roper
on Jan 21
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The combination of TPL2 knockdown and TNFα causes synthetic lethality via caspase-8 activation in human carcinoma cell lines.

Serebrennikova OB, Paraskevopoulou MD, Aguado-Fraile E, Taraslia V, Ren W, Thapa G, Roper J, Du K, Croce CM, Tsichlis PN. The […]
by Jatin Roper
on Jan 21
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Epithelial NOTCH signaling rewires the tumor microenvironment of colorectal cancer to drive poor-prognosis subtypes and metastasis.

Jackstadt R, van Hooff SR, Leach JD, Cortes-Lavaud X, Lohuis JO, Ridgway RA, Wouters VM, Roper J, Kendall TJ, Roxburgh […]
by Jatin Roper
on Jan 5
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Gut Organoids: Mini-Tissues in Culture to Study Intestinal Physiology and Disease.

Almeqdadi M, Mana MD, Roper J*, Yilmaz ÖH. Gut Organoids: Mini-Tissues in Culture to Study Intestinal Physiology and Disease. Am […]
by Jatin Roper
on Jan 5
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Single Dose Aspirin Prior To Fecal Immunochemical Testing Does Not Increase Sensitivity for Advanced Colorectal Neoplasia.

Sullivan B, Roper J. Single Dose Aspirin Prior To Fecal Immunochemical Testing Does Not Increase Sensitivity for Advanced Colorectal Neoplasia. […]
by Jatin Roper
on Jan 5
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Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium.

Pentinmikko N, Iqbal S, Mana M, Andersson S, Cognetta AB, Suciu RM, Roper J, Luopajärvi K, Markelin E, Gopalakrishnan S, […]
by Jatin Roper
on Jan 5
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Novel Three-Dimensional Cultures of Patient-Derived Cancer and Tumor Immune Cells.

Roper J, Shen X. Novel Three-Dimensional Cultures of Patient-Derived Cancer and Tumor Immune Cells. Gastroenterology. 2019 Jul;157(1):260–1. PMID: 31136743
by Jatin Roper
on Jan 5
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Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice.

Koh GY, Kane A, Lee K, Xu Q, Wu X, RoperJ, Mason JB, Crott JW. Parabacteroides distasonis attenuates toll-like receptor […]
by Jatin Roper
on Jan 5
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Myxedema Ascites: An Unusual Presentation of Uncontrolled Hypothyroidism.

Dhingra R, Rai P, Sieker J, RoperJ. Myxedema Ascites: An Unusual Presentation of Uncontrolled Hypothyroidism. Cureus. 2018 May 14;10(5):e2627. PMID: […]
by Jatin Roper
on Jan 5
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Colonoscopy-based colorectal cancer modeling in mice with CRISPR-Cas9 genome editing and organoid transplantation.

Roper J*, Tammela T, Akkad A, Almeqdadi M, Santos SB, Jacks T, Yilmaz ÖH*. Colonoscopy-based colorectal cancer modeling in mice […]
by Jatin Roper
on Jan 5
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