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Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.

Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio II, Giannopoulou EG, Rago C, Muley A, Asara JM, Paik J, Elemento O, Chen Z, Pappin DJ, Dow LE, Papadopoulos N, Gross SS, Cantley LC.

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.

Science. 2015 Dec 11;350(6266):1391–6. PMID: 26541605, PMCID: 4778961

2015

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