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© 2019

WRN helicase is a synthetic lethal target in microsatellite unstable cancers.

Chan EM, Shibue T, McFarland JM, Gaeta B, Ghandi M, Dumont N, Gonzalez A, McPartlan JS, Li T, Zhang Y, Liu JB, Lazaro JB, Gu P, Piett CG, Apffel A, Ali SO, Deasy R, Keskula P, Ng RWS, Roberts EM, Reznichenko E, Leung L, Alimova M, Schenone M, Islam M, Maruvka Y, Liu Y, Roper J, Raghavan S, Giannakis M, Tseng Y, Nagel ZD, D’Andrea A, Root DE, Boehm JS, Getz G, Chang S, Golub TR, Tsherniak A, Vazquez F, Bass AJ. 

WRN helicase is a synthetic lethal target in microsatellite unstable cancers. 

Nature. 2019 Apr;568(7753):551–6. PMID: 30971823

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